Are there direct flights from Tocumen (PTY) to Madrid (MAD)?

Yes. 9 direct route option(s) are currently listed for PTY to MAD.

Are one-stop or two-stop connections available from Tocumen to Madrid?

No connecting itineraries are currently listed in this dataset.

Route intelligence for PTY → MAD: direct flights, stopover options, and timetable coverage in one place.

9 direct option(s) across 9 airline(s) · 8,157 km route distance.

Open each airline route-map page to compare broader network depth before committing to a nonstop or one-stop strategy.

Published flight numbers: CM8106, EY7511, HU8226, MU4993, UX56

Published schedule snapshot may be stale

Flight number: CM 8106

Operating days: 1, 2, 3, 4, 5, 6, 7

Compare nearby alternatives and airline networks to decide whether a direct trip, one-stop connection, or reverse search gives you better options.

Compare direct duration with one-stop total duration before committing to a fare.
Check inbound alternatives on flights to MAD when return timing is important.
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